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Purine (C₅H₄N₄)

Purine (C₅H₄N₄)

A heterocyclic aromatic organic compound, its derivatives include guanine and adenine.

Chemistry

Keywords

purine, nitrogen-containing organic compound, heterocyclic compound, heteroatom, purine skeleton, guanine, adenine, DNA, nucleic acid, nucleotide, RNA, base pair, caffeine, theophylline, uric acid, pyrimidine, imidazole, organic chemistry, chemistry, biology, biochemistry

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Scenes

Skeleton and bases

  • purine skeleton
  • adenine
  • guanine

Purine C₅H₄N₄

Information

Molar mass: 120.11 g/mol

Melting point: 216 °C

Properties

Purine consists of an imidazole ring fused to a pyrimidine ring. As a result, it shows their characteristics. The molecule contains three basic nitrogen atoms. Purine is a colourless, crystallised substance, it dissolves in water with a neutral pH but does not dissolve in alcohol, ether or chloroform. It forms salts with acids and bases.

Occurence and production

Purine does not occur in nature in free form, but its derivatives are important. Caffeine, theophyline, uric acid and certain nucleobases are purine derivatives. Nucleic acids and other nucleotide compounds are made up of organic bases containing nitrogen. Adenine and guanine are derivatives of purine. Purine is manufactured by heating formamide under appropriate conditions or it is synthesised from 4,5 diaminopyrimidine.

Skeleton

Adenine

Guanine

Narration

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